Product: TA319208Artemis antibody
Quantity: 0.1 mg
Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Goat
Isotype:
CAS NO: 24292-60-2 Product: NADP (disodium salt)
Shipping to: Europe, USA/Canada
Immunogen: This antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross-link repair 1C).GeneID:64421
Application: This antibody has been tested for use in ELISA (1/10,000-1/20,000), Immunohistochemistry (1/1,000) and Western blotting (1/500-1/2,000). Reactivity in other immunoassays is unknown.This antibody detects a band of approximately 90 kDa (Predicted Molecular
Background: Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNAPKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical fo
Concentration: 1.2 mg/ml (by UV absorbance at 280 nm)
Storage: Store vial at -20°C. For extended storage aliquot contents and freeze at -20°C or below.Dilute only prior to immediate use.Avoid cycles of freezing and thawing.Shelf life: one year from despatch.
Buffer System: 0.02M Potassium Phosphate, 0.15M Sodium Chloride, pH 7.2, with 0.01 %(w/v) Sodium Azide as preservative.
Preservatives:
State: Liquid (sterile filtered) purified Ig fraction.Aff – Purified
Specifictiy: This antibody detects a band of the appropriate size in a number of different cell lines. However, it does not detect a band in cell lines that do not express ARTEMIS, such as the cell line CJ and in an hTERT line.