‘ coordinate is the percentage of roles (s)he accepted for each category. Scatterplots are for (a) ordinary favorable roles, (b) extraordinary favorable roles, (c) ordinary unfavorable roles, and (d) extraordinary unfavorable roles. SPQ, schizotypal personality questionnaire.** ** * ** * ** **Reaction Times (ms)Percentage of accepted roles70 60 50 40 30 20 101180 1160 1140 1120 1100 1080 1060 1040 1020 1000 980 960 940 920**Ordinary FavorableOrdinary Extraordinary Unfavorable Favorable Category combinations High SPQ scorersExtraordinary UnfavorableOrdinary FavorableExtraordinary Ordinary Favorable Unfavorable Category combinations High extraordinary role acceptersExtraordinary UnfavorableLow SPQ scorersLow extraordinary role acceptersAcceptanceRejectionFigure 2. Percentages of order Chaetocin social roles accepted in each category for high- and low-SPQ scorers and standard errors (vertical bars) for the 203 participants. *P o0.05, **P o0.0001. SPQ, schizotypal personality questionnaire.Figure 3. Mean reaction times and standard errors (vertical bars) for accepted (plain rectangles) and rejected (crosshatched rectangles) social roles for high and low extraordinary roles accepters. *Po 0.05.(i.e., bizarre behavior, thought disorders, unusual thoughts, poor insight, and difficulty in abstract thinking).16 In accordance with that view, the multiple regression suggested that the tendency to accept ordinary favorable roles had some protective effect againstnpj Schizophrenia (2016)schizotypal traits. Across all the categories, individuals with higher SPQ scores accepted more social roles than those with lower scores. All these results are reminiscent of the numerous anecdotes, so often published in the media, about thePublished in AZD0156 chemical information partnership with the Schizophrenia International Research SocietyExtraordinary roles and schizotypy AL Fernandez-Cruz et al5 disorganization of famous artists and the extraordinary roles they perform in society, now and in the past.17 On the other hand, works, such as the study of Twomey et al.,18 link psychoticism to openness to experience, sensation-seeking and creativity. Similarly, it was observed that, among writers and actors, scores for psychoticism were higher than among less `creative’ individuals19 and Andreasen noted in 1996 (ref. 20) that highly creative people had higher scores on measures of psychopathology than less creative people. In our case, this is akin to individuals who accept a lesser percentage of extraordinary social roles having lower SPQ scores. Further supporting the drive hypothesis, high accepters of extraordinary roles appeared `more enthusiast’ at accepting roles and more reluctant at rejecting them as they took less times for acceptances and more times for rejections than low accepters. This could be related to a higher baseline level of activation of the brain representations of these roles in the participants with higher SPQ scores. These results were obtained in a sample of the general population. Given the low frequency of schizotypy and of schizophrenia in that population, it is highly unlikely that those who accepted more extraordinary roles did it as a consequence of some pre-existing schizophrenia factors. One could eliminate an effect of the cognitive deficits found in the continuum going from normality to schizophrenia via schizotypy.9?3,21 In the task, these deficits would have induced longer reaction times for those who accepted more extraordinary roles or for the subgroup with higher SPQ.’ coordinate is the percentage of roles (s)he accepted for each category. Scatterplots are for (a) ordinary favorable roles, (b) extraordinary favorable roles, (c) ordinary unfavorable roles, and (d) extraordinary unfavorable roles. SPQ, schizotypal personality questionnaire.** ** * ** * ** **Reaction Times (ms)Percentage of accepted roles70 60 50 40 30 20 101180 1160 1140 1120 1100 1080 1060 1040 1020 1000 980 960 940 920**Ordinary FavorableOrdinary Extraordinary Unfavorable Favorable Category combinations High SPQ scorersExtraordinary UnfavorableOrdinary FavorableExtraordinary Ordinary Favorable Unfavorable Category combinations High extraordinary role acceptersExtraordinary UnfavorableLow SPQ scorersLow extraordinary role acceptersAcceptanceRejectionFigure 2. Percentages of social roles accepted in each category for high- and low-SPQ scorers and standard errors (vertical bars) for the 203 participants. *P o0.05, **P o0.0001. SPQ, schizotypal personality questionnaire.Figure 3. Mean reaction times and standard errors (vertical bars) for accepted (plain rectangles) and rejected (crosshatched rectangles) social roles for high and low extraordinary roles accepters. *Po 0.05.(i.e., bizarre behavior, thought disorders, unusual thoughts, poor insight, and difficulty in abstract thinking).16 In accordance with that view, the multiple regression suggested that the tendency to accept ordinary favorable roles had some protective effect againstnpj Schizophrenia (2016)schizotypal traits. Across all the categories, individuals with higher SPQ scores accepted more social roles than those with lower scores. All these results are reminiscent of the numerous anecdotes, so often published in the media, about thePublished in partnership with the Schizophrenia International Research SocietyExtraordinary roles and schizotypy AL Fernandez-Cruz et al5 disorganization of famous artists and the extraordinary roles they perform in society, now and in the past.17 On the other hand, works, such as the study of Twomey et al.,18 link psychoticism to openness to experience, sensation-seeking and creativity. Similarly, it was observed that, among writers and actors, scores for psychoticism were higher than among less `creative’ individuals19 and Andreasen noted in 1996 (ref. 20) that highly creative people had higher scores on measures of psychopathology than less creative people. In our case, this is akin to individuals who accept a lesser percentage of extraordinary social roles having lower SPQ scores. Further supporting the drive hypothesis, high accepters of extraordinary roles appeared `more enthusiast’ at accepting roles and more reluctant at rejecting them as they took less times for acceptances and more times for rejections than low accepters. This could be related to a higher baseline level of activation of the brain representations of these roles in the participants with higher SPQ scores. These results were obtained in a sample of the general population. Given the low frequency of schizotypy and of schizophrenia in that population, it is highly unlikely that those who accepted more extraordinary roles did it as a consequence of some pre-existing schizophrenia factors. One could eliminate an effect of the cognitive deficits found in the continuum going from normality to schizophrenia via schizotypy.9?3,21 In the task, these deficits would have induced longer reaction times for those who accepted more extraordinary roles or for the subgroup with higher SPQ.