Product: AM05286PU-NCaspase-8 / FLICE antibody
Quantity: 0.1 mg
Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
Presentation: Purified
Clonality: Monoclonal
Host: Mouse
Isotype: IgG
CAS NO: 266359-83-5Apoptosis inhibitors
Shipping to: Worldwide
Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human capase-8 protein and mouse myeloma cells.GeneID:841
Application: Western Blot.Positive Control: MCF-7 cell lysates.
Background: Caspases are key effectors of programmed cell death. They are synthesized as inactive proenzymes which are activated by cleavage at a specific aspartate residue to form two subunits. These subunits are normally linked together by a linker which may be i
Concentration: Lot specific
Storage: Store the antibody at -20°C.Avoid repeated freezing and thawing.Shelf life: One year from despatch.
Buffer System: PBS containing 0.08% Sodium Azide as preservative.
Preservatives:
State: Liquid (sterile filtered) purified IgG fractionPurified
Specifictiy: This antibody detects proenzyme form of human Caspase-8 by Western blot analysis as well as one of the cleavage products.

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