Product: AP00055PU-NCaspase-8 / FLICE (active) antibody
Quantity: 0.1 mg
Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
Presentation: Purified
Clonality: Polyclonal
Host: Rabbit
Isotype:
CAS NO: 273404-37-8c-Myc inhibitors
Shipping to: Worldwide
Immunogen: Synthetic peptide surrounding the cleavage site of humanCaspase-8GeneID:841
Application: Western Blot: 0.5-4 μg/ml.Immunohistochemistry: 10-20 mg/ml.
Background: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro-enzyme. Activation of caspase-8 involves a two-step proteolysis: the cleavage of caspase-8
Concentration: 0.5 mg/ml
Storage: Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: PBS, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Preservatives:
State: Liquid purified IgPurified
Specifictiy: The affinity purified antibody mainly detects the 26 kDa fully cleaved fragment and the 35-43 kDa intermediate of caspase-8 in apoptotic samples.

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