Product Name :
Lithium bis(trimethylsilyl)amide, 0.9-1.1M in hexane, packaged under Argon in resealable ChemSeal™ bottles
Synonym:
IUPAC Name :
lithium(1+) bis(trimethylsilyl)azanide
CAS NO.:
4039-32-1
Molecular Weight :
Molecular formula:
C6H18LiNSi2
Smiles:
[Li+].Catechin C[Si](C)(C)[N-][Si](C)(C)C
Description:
Lithium bis(trimetylsilyl)amide is used as a strong base in organic synthesis and as catalysts in polymerization reactions. It is also used to form various organolithium compounds such as acetylides and lithium enolates. It is a base employed in generating enolates for preparation of lactone precursors, pyranones and cyclohexanes.Alirocumab (anti-PCSK9) Further, it is used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines.PMID:27108903 In addition, it is used in a three-step synthesis of disubstituted 1,2,5-thiadiazoles.