Product: AM00178PU-NCaspase-8 / FLICE (10 kDa subunit) antibody
Quantity: 0.1 mg
Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
Presentation: Aff – Purified
Clonality: Monoclonal
Host: Mouse
Isotype: IgG1
CAS NO: 1029044-16-3ADC Linker inhibitors
Shipping to: Worldwide
Immunogen: Synthetic peptide derived from the amino-terminal sequence of p10 of human caspase-8GeneID:841
Application: Western Blot: 0.5-4 μg/ml.Immunoprecipitation: 10 μg/ml.
Background: Caspase-8, a member of the caspase-family of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase-8 is synthesized as inactive pro-enzyme and activation of the enzyme involves proteolytic cleavage that leads to the releas
Concentration: 0.2 mg/ml
Storage: Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: PBS containing 50% Glycerol, 1% BSA, and 0.02% Thimerosal.
Preservatives:
State: Liquid purified IgG fraction.Aff – Purified
Specifictiy: Detects the 10 kDa small subunit of caspase-8. The antibody does not detect the full-length of Caspase-8.