Product: AP06376PU-NCaspase-8 / FLICE antibody
Quantity: 0.1 mg
Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype:
CAS NO: 763113-22-0DAPK inhibitors
Shipping to: Worldwide
Immunogen: Synthetic peptide, corresponding to amino acids 312-368 of Human Caspase-8.GeneID:841
Application: Western blot: 1/500-1/1000.Immunohistochemistry on paraffin sections: 1/50-1/200.
Background: Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; ini
Concentration: 1.0 mg/ml
Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Phosphate buffered saline (PBS), pH 7.2.
Preservatives: 0.05% sodium azide
State: Liquid purified Ig fractionAff – Purified
Specifictiy: This antibody detects endogenous levels of Caspase 8 protein.(region surrounding Thr341)