Product: AP08917PU-NCaspase-6 antibody
Quantity: 50 µl
Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2
Presentation: Purified
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
CAS NO: 697235-38-4Medchemexpress
Shipping to: Worldwide
Immunogen: Synthetic peptide KLH coupled corresponding to residues surrounding the cleavage site of Caspase-6.GeneID:839
Application: ELISA.Western blot: 1/1000.Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Background: Caspase 6 is involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Caspase 3 and Caspase 6 are the major active c
Concentration: 0.25 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: 10 mM HEPES, pH 7.5, 150 mM Sodium Chloride containing 0.1 mg/ml BSA and 50% Glycerol.
Preservatives: None
State: Liquid purified Ig fraction.Purified
Specifictiy: Thisa antibody recognizes endogenous levels of both full length Caspase-6 (35kD) and the small subunit of Caspase-6 resulting from cleavage at Asp194 (15kD).This antibody does not recognize other Caspases.