Product: AP23608PU-NBRE / BRCC45 (9-338) antibody
Quantity: 50 µl
Synonyms: BRCA1-A complex subunit BRE, BRCA1/BRCA2-containing complex subunit 45, BRCC45, BRE, Brain and reproductive organ-expressed protein
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype:
CAS NO: 57-83-0 Product: Progesterone
Shipping to: Worldwide
Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 9 and 338 of BREGeneID:9577Remarks:Amino acid sequence homology: mouse (99%), rat (98%), bovine (99%), zebrafish (85%)
Application: Immunofluorescence: 1/100 – 1/200.Western Blot: 1/500 – 1/3000.Immunohistochemistry on paraffin sections: 10 µg/ml.
Background: Component of the BRCA1-A complex, a complex that specifically recognizes Lys-63-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRC
Concentration: 1.0 mg/ml
Storage: Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: 0.1 M Tris-glycine, pH 7.0 containing 10% Glycerol and 0.01% Thimerosal
Preservatives:
State: Liquid purfied Ig fractionAff – Purified
Specifictiy: This antibody reacts to human Brain And Reproductive Organ-expressed Protein (BRE) at aa 9-228.