Product: AP55803PU-SATF2 pSer472 antibody
Quantity: 50 µl
Synonyms: ATF-2, Activating transcription factor 2, CRE-BP1, CREB-2, CREB2, CREBP1, Cyclic AMP-dependent transcription factor ATF-2, Cyclic AMP-responsive element-binding protein 2, HB16, cAMP response element-binding protein CRE-BP1, cAMP-dependent transcription f
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype:
CAS NO: 1428569-85-0 Product: GDC-0339
Shipping to: Worldwide
Immunogen: Peptide sequence around phosphorylation site of Serine 472 (E-A-V(p)-A-T) derived from Human ATF-2 (KLH-conjugated)GeneID:1386
Application: Immunohistochemistry on paraffin sections: 1:50~1:100 .
Background: Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferential
Concentration: 1.0 mg/ml
Storage: Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Preservatives:
State: Liquid Ig fractionAff – Purified
Specifictiy: The antibody detects endogenous levels of ATF-2 only when phosphorylated at serine 472.