Product: AP55805PU-SBRCA1 / RNF53 pSer1457 antibody
Quantity: 50 µl
Synonyms: Breast cancer type 1 susceptibility protein, RING finger protein 53
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype:
CAS NO: 1312991-76-6 Product: Ro 25-6981 (Maleate)
Shipping to: Worldwide
Immunogen: Peptide sequence around phosphorylation site of Serine 1457 (L-T-S(p)-Q-K) derived from Human BRCA1 (KLH-conjugated)GeneID:672
Application: Western blot: 1:500~1:1000.
Background: The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Acts by mediating ubiquitin E3 ligase activity that is required for its tu
Concentration: 1.0 mg/ml
Storage: Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Preservatives:
State: Liquid Ig fractionAff – Purified
Specifictiy: The antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 1457.