Product: SP2146PSCaspase-1 (C-term) antibody
Quantity: 50 µg
Synonyms: CASP-1, CASP1, ICE, IL1BC, IL1BCE, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
Presentation: Purified
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Shipping to: Worldwide
Immunogen: A 16 amino acid peptide located near human Caspase-1 carboxy terminus.GeneID:834
Application: Western blot: 0.5 µg – 1.0 µg/ml.Immunohistochemistry on paraffin sections: 0.5 µg – 1.0 µg/ml; This product does not require protein digestion pre-treatment of paraffin embedded sections e.g. trypsin or pronase prior to staining.Recommended Positive Cont
Background: Caspase-1 is an intracellular cysteine protease, identified as a mammalian homologue toC. elegans cell death gene (ced-3). Caspase-1 has been classified as an inflammatory, rather than apoptotic caspase, due to its essential role in the cleavage of the in
Concentration: 1.0 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: PBS containing 0.02% Sodium Azide
State: Liquid purified IgGPurified
Specifictiy: This antibody recognises an epitope within the C-terminal region (CT) of Caspase-1, otherwise known as IL-1Beta converting enzyme. This antibody detects a cleaved subunit band of approximately 21 kDa in heart cell lysates (predicted precursor MWT 45.2kDa)

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