290 (82.six) 50 (82.0) 247 (85.2) (eight.0) 43 (four.eight) 0.79(0.38.64) .00 eight (33.6) 233 (66.4) 07 (90.7) 90 (8.5) (9.3) 43 (8.5) two.20 (.09.45) .0.Being concerned HIV may well pose a threat to members of the family Yes
290 (82.six) 50 (82.0) 247 (85.2) (eight.0) 43 (4.8) 0.79(0.38.64) .00 8 (33.6) 233 (66.4) 07 (90.7) 90 (eight.five) (9.three) 43 (8.5) two.20 (.09.45) .0.Getting concerned HIV may possibly pose a threat to family members Yes No 268 (76.8) 82 (23.2) 229 (85.4) 67 (eight.7) 39 (four.six) 5 (8.3) .32(0.68.53) .0.Sex with HIVpositive partner in previous six months Yes No 295 (84.0) 56 (six.0) 253 (85.eight) 44 (78.6) 42 (four.two) two (2.4) .64(0.80.37) .0.Frequency of condom use in preceding 6 months Just about every time The majority of the time Occasionally Never 236 (80.0) two (7.) 3 (4.four) 25 (8.5) 20 (85.2) 20 (95.2) two (92.three) 20 (80.0) 35 (4.eight) (four.8) (7.7) five (20.0) .00 3.48(0.456.79) two.09(0.266.58) 0.70 (0.25.98)0.0.23 0.49 0.50 0.Selfperceived likelihood of contracting HIV from HIVpositive companion Most likely Unlikely 09 (3.) 242 (68.9) 0 (92.7) PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/20874419 96 (8.0) eight (7.3) 46 (9.0) 2.96 (.35.52) .Abbreviations: HIV, human immunodeficiency virus; AIDS, acquired immune deficiency syndrome; PrEP, preexposure prophylaxis; CI, self-assurance interval; OR, odds ratio. doi:0.37journal.pone.0067392.tPLOS One plosone.orgWillingness to utilize PrEP in HIVDiscordant CouplesTable four. Partnership involving awareness ofuse ofattitudes toward PrEP and willingness to work with PrEP.Willing to utilize oral PrEP Variables N Yes, n No, n, OR (95 CI)P value0.Ever heard of vaginal microbicides Yes No Ever heard of PEP Yes No Ever heard of PrEP Yes No 0 (two.8) 34 (97.two) 8 (80.0) 289 (84.eight) 2 (20.0) 52 (five.two) 0.72(0.five.49) .00 34 (9.7) 37 (90.three) 28 (82.4) 269 (84.9) 6 (7.6) 48 (5.) 0.83 (0.33.2) .00 27 (7.7) 324 (92.3) 26 (96.3) 27 (83.6) (three.7) 53 (6.four) 5.09 (0.688.29) .0.0.Ever taken medicine to prevent sexually transmitted disease Yes No 7 (2.0) 344 (98.0) six (85.7) 29 (84.6) (four.three) 53 (5.4) .09 (0.three.26) .0.Worrying about being discriminated against by other people on account of oral PrEP use Yes No 92 (54.7) 59 (45.three) 45 (75.5) 52 (95.6) 47 (24.5) 7 (four.4) .00 7.04 (three.086.67)0.Abbreviations: PEP, postexposure prophylaxis; PrEP, preexposure prophylaxis; CI, self-assurance interval; OR, odds ratio. doi:0.37journal.pone.0067392.tWillingness to make use of oral PrEP and concerns related to its useA total of 297 participants (84.6 ) were CAY10505 web prepared to use oral PrEP if confirmed both powerful and secure. The remaining 54 participants (5.4 ) have been unwilling to work with oral PrEP mainly because three (57.4 ) believed they had been at no threat of contracting HIV, or 28 (five.9 ) have been concerned about its safety, or 2 (22.two ) doubted its efficacy. Amongst participants willing to work with oral PrEP, 258 (86.eight ) were concerned about its efficacy, 249 (83.eight ) had been concerned about its security, 90 (64.0 ) have been concerned about its expense, and 45 have been concerned about its availability (5.2 ). Concerning social concerns, 3 (38.0 ) participants had no fear of disclosing their use of PrEP to other individuals.Multivariate logistic regression evaluation of components connected with willingness to use oral PrEPIn multivariate logistic regression analysis, willingness to use oral PrEP was coded as “”, and unwillingness to work with oral PrEP was coded as “0”. Variables that had been considerable (P,0.two) within the univariate evaluation have been entered in to the initial multivariate logistic model; these variables integrated “age”, “ethnicity”, “monthly household income”, “having a fantastic awareness of HIVAIDS”, “sex with HIVpositive partner in the preceding six months”, “awareness of vaginal microbicides”, “it is difficult to avert HIVAIDS when cohabiting with a HIVpositive partner”, “selfperceived likelihood of contracting HIV from an HIVpositiveAcceptability of oral PrEP in.