Ersity of New South Wales, Sydney, New South Wales, Australia Institute of Psychiatry, King’s College London, London, UK Department of Psychiatry, Universitde Montr l, Montreal, Quebec, Canada Correspondence to Dr Nicola C Newton; [email protected] Substance use amongst young persons continues to become a significant public wellness concern.The European College Survey Project on Alcohol and other Drugs (EPSAD) examined substance use in over studentsfrom European countries, like the UK, and discovered alcohol and cannabis to become one of the most generally made use of licit and illicit drugs, respectively.On average, of students reported drinking alcohol at the very least after in their lifetime, reported drinking alcohol in the past month, and reported heavy episodic drinking in the past month (defined as or far more drinks on one particular occasion).Lifetime cannabis use was reported by of respondents with rates closer to one particular in 4 for UK students.The high prevalence of use amongst young men and women is a matter of distinct concern considering that such behaviours are linked with important burden of disease, social charges and increased risk of creating substance use disorders and comorbid PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21438884 mental overall health issues.To alleviate this burden and lessen the occurrence and price of such difficulties, prevention is crucial and requires to be initiated early just before dangerous patterns of drug use are established and start to cause disability.Newton NC, Conrod PJ, Rodriguez DM, et al.BMJ Open ;e.doi.bmjopenOpen Access Though prevention techniques do exist, analysis has not been able to regularly demonstrate that universal schoolbased drug prevention is productive in minimizing actual substance use, and till now there have been no good evaluations of successful universal interventions to prevent substance use within the UK.That is because the effectiveness of schoolbased prevention is frequently compromised by obstacles linked with programme implementation and dissemination, and by the adoption of abstinenceas opposed to the successful harmminimisation method to prevention.The universal internetbased Climate Schools Alcohol and Cannabis course was developed to overcome these obstacles and aims to prevent alcohol and cannabis use and related harms amongst adolescents.The Climate Schools programme is based around the powerful harmminimisation approach to prevention and uses cartoon Sakuranetin Protocol storylines to engage and keep student interest.The programme is facilitated by the web, which guarantees total and constant delivery even though ensuring high implementation fidelity.The programme is made to match inside the college overall health curriculum and be implemented among yearolds ahead of substantial exposure to alcohol and drug use happens, and consists of two sets of six lessons delivered approximately months apart more than the school year.The efficacy in the Climate Schools programme has been established making use of a cluster randomised controlled trial (RCT) in secondary schools in Australia (n).Final results from the RCT demonstrate that, compared together with the manage group, students inside the intervention group showed important improvements in alcohol and cannabis expertise, reductions in typical alcohol consumption and binge drinking, along with a reduction in frequency of cannabis use as much as months following the intervention.Moreover, evaluations with the internetbased programme by teachers and students inside the trial had been very constructive.Especially, of students reported that the data delivered was e.