Species: Human Expressing host: HEK293 cells Description: Recombinant Biotinylated Human Latent TGF beta 1/TGFB1 Protein is expressed from Expi293 with His tag and Avi tag at the N-terminal.It contains Leu30-Ser390(C33S). Tag: N-His&Avi Purity: > 95% as determined by Tris-Bis PAGE> 93% as determined by HPLC Endotoxin: Less than 1EU per g by the LAL method. Storage Store the lyophilized protein at -20C to -80C for long term.
After reconstitution, the protein solution is stable at -20C for 3 months, at 2-8C for up to 1 week.Unopened freeze-dried powder,Store at -20 to -80 °C for twelve months
Redissolution: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.Redissolution:Store at -20 to -80 °C,avoid repeated freeze thaw cycles
Background Information : Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein . A furin?like convertase processes the proprotein to generate an N?terminal 249 aa latency?associated peptide (LAP) and a C?terminal 112 aa mature TGF? beta 1. Disulfide?linked homodimers of LAP and TGF? beta 1 remain non?covalently associated after secretion, forming the small latent TGF? beta 1 complex . Swiss Prot P01137 Alias: CEDLAP; DPD1; TGF beta1; TGFB; TGFB1; TGFbeta; TGF-beta-1MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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